A microfluidic toolbox for cell fusion

A Novel Toolbox for Generating Realistic Biological Cell Geometries for Electromagnetic Microdosimetry

Researchers in bioelectromagnetics often require realistic tissue, cellular and sub-cellular geometry models for their simulations. However, biological shapes are often extremely irregular, while conventional geometrical modeling tools on the market cannot meet the demand for fast and efficient construction of irregular geometries. We have designed a free, user-friendly tool in MATLAB that comb...

A fusion toolbox for sensor data fusion in industrial recycling

Information from different sensors can be fused in various ways. It is often difficult to choose the most suitable method for solving a fusion problem. In a measurement situation, the measured signal is often corrupted by disturbances (noise, etc.). It is, therefore, meaningless to compare crisp values without the corresponding uncertainty intervals. This paper describes a toolbox including nin...

Electromembrane Processes, a Toolbox for Advanced Separations

Deformability-based microfluidic cell pairing and fusion.

We present a microfluidic cell pairing device capable of sequential trapping and pairing of hundreds of cells using passive hydrodynamics and flow-induced deformation. We describe the design and operation principles of our device and show its applicability for cell fusion. Using our device, we achieved both homotypic and heterotypic cell pairing, demonstrating efficiencies up to 80%. The platfo...

Microfluidic systems: a new toolbox for pluripotent stem cells.

Conventional culture systems are often limited in their ability to regulate the growth and differentiation of pluripotent stem cells. Microfluidic systems can overcome some of these limitations by providing defined growth conditions with user-controlled spatiotemporal cues. Microfluidic systems allow researchers to modulate pluripotent stem cell renewal and differentiation through biochemical a...